The KYKLOS 4.0 Ecosystem will include a core set of data management and analytics tools to fuse data coming from different disjoint levels of the factory lifecycle. These tools will detect complex patterns of manufacturing processes and provide useful information both for supporting short-term analysis (e.g. optimization, scheduling, monitoring of KPIs) and refinement of long-term manufacturing strategies (reconfiguration, new processes). Analytics, innovative simulation tools and machine learning techniques will provide unified, dynamic, indicators of all aspects of design and manufacturing stages will be available to decision makers at various levels e.g. production line designers, engineers, shop floor managers, plant operators, supply chain.